|Lectins are bioactive proteins or glycoproteins that are ubiquitous
in nature and often express exquisite specificity for binding to carbohydrates,
particularly carbohydrate sequences that occur on the surface of living
cells. Because all cells are “sugar coated,” it is not surprising
that lectins and carbohydrates are important partners in biological
recognition and the deployment of a multitude of biological functions.
One biological function that Lectin Labs is intensely investigating is based on the fundamental principal that microbes must first attach to host cells in order to cause an infectious disease. Irrespective of whether the microbial receptors the pathogens bind to are proteins or carbohydrates - or both - the Company has found that targeting sugar-coated infectious agents with specific plant lectins, which bind with various high-affinities, have severe consequences that ultimately lead to the treatment and/or prevention of many topical diseases.
The emergence of antibiotic and drug resistant microbes makes it vital to find new strategies for the treatment and prevention of diseases caused by resistant microorganisms. Through extensive laboratory investigations (high through-put screening, molecular and kinetic analyses), preclinical and clinical studies, Lectin Labs is providing proven alternative approaches against the war on resistant microorganisms.